Early Cancerous Changes in Lower Genital Tract of Women- Update-24.2.19-Cell level changes
As promised, we will continue our discussion on Preinvasive Lesions/Precancerous of The Lower Genital Tract of Women’.
-These lesions are a spectrum ranging from mildly cytoplasmic & nuclear (cell level) changes to severe dysplasia (severe derangement).
-There is no invasion (penetration) through basement membrane which would then characterize as invasive cancer.
–Grading ( categorisation ) is done by measuring proportion of epithelium ( lining ) affected from basement membrane upwards.
– If it is affecting lower 1/3 rd, it is grade 1 or mild dysplasia.
-Involvement up to middle third is grade 2 or moderate dysplasia.
– Extension in to upper third is grade 3 or severe dysplasia.
– Full thickness involvement is known as carcinoma in situ.
– So, friends, in next update of this series will discuss in detail about some other aspect of this topic.
Dr Himani Gupta
Gynaecologist & Obstetrician
Director-My Gynaec World
Official Head Quarter
Mother ‘n’ Care Clinic
Row House F 44/32
Near Shivaji Chowk
Sector 12-Kharghar, Navi Mumbai