Early Cancerous Changes in Lower Genital Tract of Women- Update-24.2.19-Cell level changes

Early Cancerous Changes in Lower Genital Tract of Women- Update-24.2.19-Cell level changes

Hello friends,

As promised, we will continue our discussion on Preinvasive Lesions/Precancerous of The Lower Genital Tract of Women’.

-These lesions are a spectrum ranging from mildly cytoplasmic & nuclear (cell level) changes to severe dysplasia (severe derangement).

-There is no invasion (penetration) through basement membrane which would then characterize as invasive cancer.

Grading ( categorisation ) is done by measuring proportion of epithelium ( lining ) affected from basement membrane upwards.

– If it is affecting lower 1/3 rd, it is grade 1 or mild dysplasia.

-Involvement up to middle third is grade 2 or moderate dysplasia.

– Extension in to upper third is grade 3 or severe dysplasia.

– Full thickness involvement is known as carcinoma in situ.

– So, friends, in next update of this series will discuss in detail about some other aspect of this topic.

By

Dr Himani Gupta

Gynaecologist & Obstetrician

Director-My Gynaec World

Official Head Quarter

Mother ‘n’ Care Clinic

Row House F 44/32

First Floor

Near Shivaji Chowk

Sector 12-Kharghar, Navi Mumbai

Ph  +91-7506027299

+91- 9820193283